000			01461cam a22002534a 4500
020			_a9781439816783 (hardcover : alk. paper)
020			_a1439816786 (hardcover : alk. paper)
082	0	0	_a572.80285
100	1		_aMacCuish, John D.
245	1	0	_aClustering in bioinformatics and drug discovery /
260			_aBoca Raton, FL : _bCRC Press, _cc2011.
300			_a214 p. : _bill. ; _e1 DVD (4 3/4 in.)
490	0		_aChapman & Hall/CRC mathematical and computational biology series
520			_a"This book presents an introduction to cluster analysis and algorithms in the context of drug discovery clustering applications. It provides the key to understanding applications in clustering large combinatorial libraries (in the millions of compounds) for compound acquisition, HTS results, 3D lead hopping, gene expression for toxicity studies, and protein reaction data. Bringing together common and emerging methods, the text covers topics peculiar to drug discovery data, such as asymmetric measures and asymmetric clustering algorithms as well as clustering ambiguity and its relation to fuzzy clustering and overlapping clustering algorithms"--Provided by publisher.
650		0	_aBioinformatics
650		0	_aDrug development.
650		0	_aCluster analysis.
650		0	_aComputational biology.
650	1	2	_aCluster Analysis.
650	1	2	_aDrug Discovery
650	2	2	_aComputational Biology.
700	1		_aMacCuish, Norah E.
942			_cBK
999			_c33743 _d33743