TY  - BOOK
AU  - Slack,Frank J.
TI  - Micro RNAs in development and cancer 
T2  - Molecular medicine and medicinal chemistry
SN  - 9781848163669 
U1  - 616.992 
PY  - 2011///
CY  - London, Hackensack, NJ
PB  - Imperial College Press, World Scientific [distributor]
KW  - Small interfering RNA
KW  - Cancer
KW  - MicroRNAs
KW  - Gene Expression Regulation
KW  - Neoplasms
KW  - Tumor Markers, Biological
N2  - "MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer."--Back cover
ER  -