Enzyme-mediated resistance to antibiotics :mechanisms, dissemination, and prospects for inhibition

Contributor(s): Bonomo, Robert A,Ed | Tolmasky, Marcelo,EdMaterial type: TextTextPublication details: Washington D.C ASM Press 2007Description: xviii,357p., [8] p. of plates : ill. (some col.)ISBN: 9781555813031Subject(s): Drug resistance in microorganisms | Microbial enzymes | Anti-Bacterial Agents | Drug Resistance, Bacterial | Enzyme Inhibitors | beta-LactamasesDDC classification: 616.9041 Summary: A vital, comprehensive overview from some of the world’s leading researchers and scholars in this field. • Discusses bβ-Lactamases and aminoglycoside-modifying enzymes as well as other enzymatic mechanisms that result in resistance. • Covers the different ways bacteria share resistance determinants, both vertically and horizontally. • Offers strategies to control the dissemination of resistance genes and to combat these highly versatile inactivating enzymes. • Serves as a resource for researchers working for clinical research laboratories, hospitals, medical schools, and applied and pharmaceutical research laboratories.
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A vital, comprehensive overview from some of the world’s leading researchers and scholars in this field.
• Discusses bβ-Lactamases and aminoglycoside-modifying enzymes as well as other enzymatic mechanisms that result in resistance.
• Covers the different ways bacteria share resistance determinants, both vertically and horizontally.
• Offers strategies to control the dissemination of resistance genes and to combat these highly versatile inactivating enzymes.
• Serves as a resource for researchers working for clinical research laboratories, hospitals, medical schools, and applied and pharmaceutical research laboratories.

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