Membrane transport mechanism : (Record no. 45112)
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000 -LEADER | |
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fixed length control field | 02127nam a2200241 4500 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
ISBN | 9783642538384 |
082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
Classification number | 571.64 |
245 00 - TITLE STATEMENT | |
Title | Membrane transport mechanism : |
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
Place of publication | Berlin |
Name of publisher | Springer verag |
Year of publication | 2014 |
300 ## - PHYSICAL DESCRIPTION | |
Number of Pages | xii, 272 pages : |
Other physical details | illustrations (some color) ; |
490 1# - SERIES STATEMENT | |
Series statement | Springer Series in Biophysics, |
520 ## - SUMMARY, ETC. | |
Summary, etc | This book provides a molecular view of membrane transport by means of numerous biochemical and biophysical techniques. The rapidly growing number of atomic structures of transporters in different conformations and the constant progress in bioinformatics have recently added deeper insights. The unifying mechanism of energized solute transport across membranes is assumed to consist of the conformational cycling of a carrier protein to provide access to substrate binding sites from either side of a cellular membrane. Due to the central role of active membrane transport there is considerable interest in deciphering the principles of one of the most fundamental processes in nature: the alternating access mechanism. This book brings together particularly significant structure-function studies on a variety of carrier systems from different transporter families: Glutamate symporters, LeuT-like fold transporters, MFS transporters and SMR (RND) exporters, as well as ABC-type importers. The selected examples impressively demonstrate how the combination of functional analysis, crystallography, investigation of dynamics and computational studies has made it possible to create a conclusive picture, or, more precisely, a molecular movie. Although we are still far from a complete molecular description of the alternating access mechanism, remarkable progress has been made from static snapshots towards membrane transport dynamics. -- |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | Biological transport. |
650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | Biological Transport |
650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | Membrane Transport Proteins |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | Biological transport. |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | Membrantransport |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | Carrier-Proteine |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | Struktur-Aktivitäts-Beziehung |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Krämer, Reinhard, |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Ziegler, Christine, |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Koha item type | BK |
952 ## - LOCATION AND ITEM INFORMATION (KOHA) | |
Withdrawn status | |
Lost status | |
Damaged status |
Collection code | Home library | Current library | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
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Stack | Kannur University Central Library | Kannur University Central Library | Stack | 21/03/2018 | 571.64 | 45790 | BK |