Micro RNAs in development and cancer
- London : Hackensack, NJ : Imperial College Press ; World Scientific [distributor], c2011
- xv, 282 p. : ill. (some col.) ;
- Molecular medicine and medicinal chemistry ; .
"MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer."--Back cover.
9781848163669 1848163665
Small interfering RNA.
Cancer.
MicroRNAs.
Gene Expression Regulation.
Neoplasms
Neoplasms
Tumor Markers, Biological.
616.992 / MIC
"MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer."--Back cover.
9781848163669 1848163665
Small interfering RNA.
Cancer.
MicroRNAs.
Gene Expression Regulation.
Neoplasms
Neoplasms
Tumor Markers, Biological.
616.992 / MIC